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Soft Tissue Tumors Part 3 - Muscle, Vascular, Nerve, Other
Benign vascular tumors
Intravascular papillary endothelial hyperplasia
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Revised: 18 July 2010, last major update July 2009
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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● Reactive, not neoplastic, representing exuberant organization and recanalization of thrombus
● In normal vessels but also varices, hemorrhoids, pyogenic granulomas, hematomas, angiosarcomas
Terminology
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● Aka Masson’s tumor
Epidemiology
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●
Sites
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● Dermis and subcutis of head and neck, lip, tongue, buccal mucosa
Features
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● Pure type: within a dilated vascular space
● Mixed type: with preexisting vascular disorder or in a hematoma
Treatment and prognosis
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Case reports
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● Case history of paranasal sinus lesion with erosion of surrounding bony structures, Archives 2000;124:1224
Clinical description
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Clinical images
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Gross description
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● Small, firm, red-blue superficial masses in skin
Gross images
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Microscopic description
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● Papillary formations with hyaline or fibrous stalks, anastomosing vascular channels, plump endothelial cells; residual organizing thrombi
● Intravascular lesion only
● No necrosis, no atypia, no atypical mitotic figures
Micro images
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Cytology description
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Cytology images
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Virtual slides
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Positive stains
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Negative stains
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Electron Microscopy
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Electron Microscopy images
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Molecular / cytogenetics
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Molecular / cytogenetics images
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Differential diagnosis
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● Angiosarcoma
Additional references
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●
End of Soft Tissue Tumors Part 3 - Muscle, Vascular, Nerve, Other > Intravascular papillary endothelial hyperplasia
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