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Skin-nontumor / Clinical Dermatology

Other dermatoses

Anetoderma

Reviewer: Cecilia Rosales, M.D., Baylor College (see Reviewers page)
Revised: 18 July 2011, last major update July 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

General
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● Benign disorder of focal loss of dermal elastic tissue, causing focal flaccid or saclike skin
● Either primary (idiopathic) arising in normal skin, or secondary arising at site of previous skin lesions

Terminology
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● Greek: Anetos means slack

Epidemiology
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● Acquired purely cutaneous disorder
● Most common in young adults, onset most often in second decade
● Affects upper trunk and proximal arms; may be widespread
● Affect both sexes equally; rare familial variant

Case reports
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● 14 year old boy with lesions on acral sites of upper and lower extremities (BMC Dermatol 2004;4:9)

Clinical description
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● Erythematous macules and urticarial plaques, progressing to flaccid, easily reduced papules
● Also fine, diffuse wrinkling
● May be accompanied by herniation into subcutaneous fat

Clinical images
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Lesion of lower leg


Various images

Microscopic description
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● No abnormality on H&E
● Elastic stains show no/marked reduction in elastic fibers of papillary and mid-reticular dermis
● Early lesions: variable perivascular and periadnexal mixed inflammatory infiltrate

Microscopic images
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H&E and elastic stains

   
H&E and elastic stains

End of Skin-nontumor / Clinical Dermatology > Other dermatoses > Anetoderma

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